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- $Unique_ID{BRK03537}
- $Pretitle{}
- $Title{Bowenoid Papulosis}
- $Subject{Bowenoid Papulosis BP Bowen's Disease Condyloma Lichen Planus}
- $Volume{}
- $Log{}
-
- Copyright (C) 1992 National Organization for Rare Disorders, Inc.
-
- 925:
- Bowenoid Papulosis
-
- ** IMPORTANT **
- It is possible that the main title of the article (Bowenoid Papulosis) is
- not the name you expected. Please check the SYNONYMS listing to find the
- alternate name and disorder subdivisions covered by this article.
-
- Synonyms
-
- BP
-
- Information on the following diseases can be found in the Related
- Disorders section of this report:
-
- Bowen's Disease
- Condyloma
- Lichen Planus
-
- General Discussion
-
- ** REMINDER **
- The Information contained in the Rare Disease Database is provided for
- educational purposes only. It should not be used for diagnostic or treatment
- purposes. If you wish to obtain more information about this disorder, please
- contact your personal physician and/or the agencies listed in the "Resources"
- section of this report.
-
- Bowenoid Papulosis is a rare sexually transmitted disorder thought to be
- caused by human papillomavirus type 16. This disorder is characterized by
- lesions that are found on the genitals of males and females. The lesions are
- reddish brown or violet in color, small, solid, raised and sometimes velvety.
-
- Symptoms
-
- Bowenoid Papulosis is a rare sexually transmitted infection that is
- characterized by lesions that are typically found on the genitals. These
- lesions may last from two weeks to several years. Females may be affected
- inside the vagina, on the clitoris, groin folds, labia major, labia minor
- and/or anus. Males may be affected on the glans, shaft and/or foreskin of
- the penis as well as the anus. The lesions found in Bowenoid Papulosis are
- usually reddish brown or violet in color, small, solid, smooth, raised and
- velvety. The lesions on females are usually darker than the lesions on
- males.
-
- Many patients with Bowenoid Papulosis often have other types of viral
- infections that precede this condition. Herpes simplex, human
- papallomavirus, viral warts, and HIV infection have been found in some
- patients with this disorder. When viewed under a microscope the Bowenoid
- Papulosis tissue structure looks like pre-invasive squamous-cell carcinoma (a
- form of cancer cells). In some cases Bowenoid Papulosis has become
- malignant.
-
- Causes
-
- Bowenoid Papulosis is a sexually transmitted disorder thought to be caused by
- human papillomavirus type 16. Other viruses as well as a suppressed immune
- system may also play a role in contracting Bowenoid Papulosis.
-
- Affected Population
-
- Bowenoid Papulosis affects males and females in equal numbers. This disorder
- is seen in sexually active adults with the average ages being 30 for males
- and 32 for females. However, Bowenoid Papulosis has been found in patients
- ranging from ages 3 to 80. It has recently been appearing in increasing
- numbers worldwide.
-
- Related Disorders
-
- Symptoms of the following disorders can be similar to those of Bowenoid
- Papulosis. Comparisons may be useful for a differential diagnosis:
-
- Bowen's Disease is characterized by a precancerous, slow growing skin
- malignancy. The major symptom is a red-brown, scaly or crusted patch on the
- skin which resembles psoriasis or dermatitis. It may occur on any part of
- the skin or in the mucous membranes. (For more information on this disorder,
- choose "Bowen's Disease" as your search term in the Rare Disease Database).
-
- Condyloma is a common infectious venereal disease that is caused by the
- human papillomavirus (HPV) and usually transmitted by direct sexual contact.
- The warts found in this disorder are small, soft, moist, pink or red
- elevations on the skin or mucous membranes of the genitals, mouth, anus or
- rectum. Typically the warts form in clusters. (For more information on this
- disorder, choose "Condyloma" as your search term in the Rare Disease
- Database).
-
- Lichen Planus is a recurrent, itchy, inflammatory eruption of the skin
- which is characterized by small, separate, angular spots that may grow
- together forming rough scaly patches. It is often accompanied by oral
- lesions. Women are most commonly affected by this disorder. The lesions are
- most commonly found on the joint surfaces of the wrists and on the legs,
- trunk, glands, penis and mucous membrane of the mouth and vagina. (For more
- information on this disorder, choose "Lichen Planus" as your search term in
- the Rare Disease Database).
-
- Therapies: Standard
-
- Patients with Bowenoid Papulosis should be monitored carefully. In some
- cases Bowenoid Papulosis may heal spontaneously (without treatment). Sexual
- activity should be limited in order to avoid infecting other people during
- the contagious stages of this disorder.
-
- Electrosurgery, cryosurgery (surgery in which the tissue is frozen with
- liquid nitrogen), and/or lazer surgery may be used to remove the lesions when
- necessary.
-
- In some milder cases the use of 5-Fluorouracil (a topical cream) has been
- successful.
-
- Therapies: Investigational
-
- Research on skin disorders is ongoing at major medical universities.
- Progress on the understanding of viral infections has increased during recent
- years, but there has been little progress in the development of new treatment
- for viral diseases.
-
- This disease entry is based upon medical information available through
- August 1992. Since NORD's resources are limited, it is not possible to keep
- every entry in the Rare Disease Database completely current and accurate.
- Please check with the agencies listed in the Resources section for the most
- current information about this disorder.
-
- Resources
-
- For more information on Bowenoid Papulosis, please contact:
-
- National Organization for Rare Disorders (NORD)
- P.O. Box 8923
- New Fairfield, CT 06812-1783
- (203) 746-6518
-
- American Social Health Association
- 100 Capitola Dr., Suite 200
- Research Triangle Park, NC 27713
- (919) 361-8400
-
- Council for Sex Information and Education
- 444 Lincoln Blvd., Suite 107
- Venice, CA 90291
-
- National Sexually Transmitted Diseases Hotline
- (800) 227-8922
-
- NIH/National Institute of Allergy and Infectious Diseases (NIAID)
- 9000 Rockville Pike
- Bethesda, MD 20892
- (301) 496-5717
-
- Centers for Disease Control (CDC)
- 1600 Clifton Road , NE
- Atlanta, GA 30333
- (404) 639-3534
-
- References
-
- CLINICAL DERMATOLOGY, 2nd Ed.; Thomas P. Habif, M.D., Editor: The C.V. Mosby
- Company, 1990. Pp. 246.
-
- BOWENOID PAPULOSIS: T.T. Rogozinski, et al.; Am Fam Physician (July,
- 1988, issue 38(1)). Pp. 161-4.
-
- BOWENOID PAPULOSIS. DEMONSTRATION OF HUMAN PAPILLOMAVIRUS (HPV) WITH
- ANTI-HPV IMMUNE SERUM: G.Y. Guillet, et al.; Arch Dermatol (April, 1984,
- issue 120(4)). Pp. 514-6.
-
- BOWENOID PAPULOSIS OF THE GENITALIA: T.R. Wade et al.; Arch Dermatol
- (March, 1979, issue 115(3)). Pp. 306-8.
-
- BOWENOID PAPULOSIS. PRESENCE OF HUMAN PAPILLOMAVIRUS (HPV) STRUCTURAL
- ANTIGENS AND OF HPV 16-RELATED DNA SEQUENCES: G. Gross et al.; Arch Dermol
- (July, 1985, issue 121(7)). Pp. 858-63.
-
- BOWENOID PAPULOSIS: J.W. LaVoo; Dis Colon Rectum (January, 1987, issue
- 30(1)). Pp. 62-4.
-
- BOWENOID PAPULOSIS OF THE MALE AND FEMALE GENETALIA: S. Obalek et al.; J
- Am Acad Dermatol (March, 1986, issue 14(3)). Pp. 433-44.
-
-